Knowledge of a foreign language helps people from different cultures exchange experiences, expertise, and ideas worldwide. It is considered a valuable asset in the professional field and may be highly useful in personal life. Foreign language classroom anxiety is a phenomenon associated with fear and nervousness that occurs in a language learning context. Foreign language classroom anxiety often leads to a decrease in overall process efficiency, motivation loss, and avoidance of language practice. The aim of this study is to investigate, whether Big Five personality traits contribute to foreign language classroom anxiety. Four hundred and fifty-two foreign language learners aged between 16 and 70 participated in the study. Participants were given а Big Five personality inventory to assess their personality traits (extraversion, agreeableness, conscientiousness, neuroticism, and openness to new experience), and a foreign language classroom anxiety scale which measures the following components: test anxiety, fear of negative evaluation, and communication apprehension. Linear regression was used as an analysis method. The results revealed that neuroticism positively predicted fear of negative evaluation, communication apprehension, and test anxiety. Extraversion negatively predicted fear of negative evaluation, communication apprehension, and test anxiety. Openness to experience also negatively predicted all three foreign language anxiety components. The results of the study suggest that knowledge of learners’ Big Five personality traits may decrease the levels of foreign language anxiety in a classroom.