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Alexandra Litvinova1, Rinat Bogdanov2
  • 1 Lomonosov Moscow State University, 1 Leninskie Gory, Moscow, 119991, Russia
  • 2 The State Budgetary Healthcare Institution of Moscow Area “Moscow's regional research clinical institute n.a. M.F. Vladimirskiy”, 61/2 Stchepkin str., Moscow, 129110, Russia

Letter Cancellation Test Performance in Healthy Subjects and Patients with Parkinson’s Disease during Aging (in Russian)

2015. Vol. 12. No. 4. P. 142–153 [issue contents]

The aim of the study is to find age characteristics of oculomotor task  performance using the Letter Cancellation Test and images of different complexity. Healthy subjects aged 14-75 years and patients with early stages of Parkinson disease (PD) aged 42-75 years took part in the study. Completion time of Letter Cancellation Test in healthy volunteers differs insignificantly with age; in patients with PD there is a tendency to perform longer on the test. Quantity of mistakes during the performance on the test by healthy volunteers on a greater degree depends on age, and patients during the search of the letter commit as much mistakes, as healthy people of their age group do. The success of performance on the task of viewing images of various levels of complexity depends on the age of the volunteers and worsens in PD. Herewith, both healthy participants of senior age and patients have better results in viewing more complex images. Thus, we found that in the conditions of complex visual environment motor function is less susceptible to age-related changes, and at the same time the ability to concentrate attention has several stages of development. In patients with PD, despite hypokinesia and oculomotor dysfunctions, cognitive component does not suffer in task performance on visual search. The results of the study can contribute to diagnostics of early dementia or cognitive dysfunctions of a light degree in people of senior age, as well as in attention deficit disorder in young age. 

Citation: Litvinova, A., & Bogdanov, R. (2015). Letter Cancellation Test Performance in Healthy Subjects and Patients with Parkinson’s Disease during Aging. Psychology. Journal of Higher School of Economics, 12(4), 142-153 (in Russian)
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