The analysis of frequency and spatial organization of cerebral cortex activity in the process of creative thinking and its comparison with functions of attention systems was carried out. Predominance of task-oriented focused attention during problem formulation, planning of its solution or critical evaluation of generated ideas is accompanied by increase of activation in cerebral cortex whereas transition to the defocused attention leads to the opposite processes of decrease of activation especially in frontal cortex which performs function of executive and supportive attention and, then, in occipital cortex which are responsible for knowledge retrieval. The resulting strategy of information selection and corresponding level of cortex activation and interaction of hemispheres is additionally defined by motivation for creative activity and by structure of intelligence which both determine the evaluated difficulty of the task.